Brain Repair of Any Injured Neural Structure (BRAINS) - Proposers' Day
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Advanced Research Projects Agency for Health (ARPA-H) is hosting a Proposers' Day for its Brain Repair of Any Injured Neural Structure (BRAINS) Exploratory Topic program. This Special Notice (SN) informs the scientific community about an upcoming Innovative Solutions Opening (ISO) focused on developing methods to regenerate in situ normal region-specific brain tissue to reverse damage and disease. ARPA-H anticipates multiple Other Transaction (OT) awards from the future ISO. Interested parties are required to submit a solution summary for the ISO.
Purpose & Scope
The BRAINS program aims to address brain damage by developing precursor tissue that can restore function, excluding organoid-based approaches. It targets various brain regions (excluding neocortex and spinal cord) and involves two technical areas: generating precursor tissue and demonstrating surgical engraftment. The Proposers' Day will provide information on technical areas, program goals, and the structure for solution summaries and proposals for the forthcoming ISO.
Contract & Timeline
- Opportunity Type: Special Notice (for Proposers' Day)
- Anticipated Awards (from ISO): Multiple Other Transaction (OT) awards
- Set-Aside: None specified
- Proposers' Day (Virtual): June 9, 2026
- Live Q&A: June 24, 2026
- Sidebars: June 25, 2026
- Proposers' Day Registration Opens: June 9, 2026, at 12:00 PM ET
- Proposers' Day Registration Closes: 48 hours before the event
- ISO Expected: No later than June 9, 2026
- Overall Response Date (for ISO): February 6, 2027
- Published: June 8, 2026
Key Requirements
Parties interested in submitting a proposal for the future BRAINS ISO are mandatorily required to submit a solution summary. No awards or funding will result directly from solution summary submissions.
Additional Notes
This Special Notice is for informational purposes only and does not constitute a formal solicitation. Full details will be provided in the forthcoming BRAINS ISO. The Proposers' Day recording will be available on the BRAINS program website.