Chemistry Support for the DTT (NIEHS) - RFI/SSN

SOL #: 75N94026R00002Sources Sought

Overview

Buyer

Health And Human Services
National Institutes Of Health
NATIONAL INSTITUTES OF HEALTH NICHD
BETHESDA, MD, 20817, United States

Place of Performance

Place of performance not available

NAICS

Research and Development in the Physical (541715)

PSC

No PSC code specified

Set Aside

No set aside specified

Timeline

1
Posted
Feb 17, 2026
2
Response Deadline
Mar 4, 2026, 10:00 PM

Qualification Details

Fit reasons
  • NAICS alignment with historical contract wins in similar service areas.
  • Scope strongly matches core technical capabilities and delivery model.
Risks
  • Past performance thresholds may require one additional teaming partner.
  • Potential clarification needed on staffing minimums before bid/no-bid.
Next steps

Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.

Quick Summary

The National Institute of Environmental Health Sciences (NIEHS), under the National Institutes of Health, has issued a combined Request for Information (RFI) and Sources Sought Notice (SSN) for Chemistry Support for its Division of Translational Toxicology (DTT). This is for market research and project planning purposes only, not a solicitation. Responses are due by March 4, 2026, at 5:00 PM EST.

Scope of Work

The NIEHS is seeking information and capability statements from organizations experienced in providing a wide range of chemistry services to support DTT research. Key areas include:

  • Logistics and Handling: Procurement, handling, and shipment of test articles and samples.
  • Characterization: Determining identity and purity of test articles.
  • Formulation: Preparation, mixing, and analysis of dose formulations.
  • Biosample Analysis: Determination of analyte concentrations in various matrices.
  • Special Studies: Activities combining or subsetting functional areas.
  • Animal Studies: Determining absorption, distribution, metabolism, and excretion (ADME) and toxicokinetic (TK) parameters.
  • Omics: Exposomics, proteomics, and metabolomics analyses.
  • In Vitro Assays: Determining in vitro ADME/toxicity of test articles.

Contract & Timeline

  • Type: Sources Sought / Request for Information (RFI/SSN)
  • Anticipated Contract Type (if awarded): Cost-Plus-Fixed-Fee, Level-of-Effort, with severable services.
  • Anticipated Duration: Up to ten years, with an additional optional six-month period.
  • Response Due: March 4, 2026, 5:00 PM EST
  • Published: February 17, 2026

Eligibility / Set-Aside

  • NAICS Code: 541715 ("Research and Development in the Physical, Engineering, and Life Sciences")
  • Small Business Size Standard: 1,000 employees or less
  • Participation: Information is sought from organizations of all business sizes.

Submission & Evaluation

Respondents are encouraged to submit feedback on the Draft Statement of Work (Attachment 2), responses to RFI questions (Attachment 3), and business information (Attachment 4). Capability statements should address the requested technical information and identify business size status. This notice is for planning purposes only; no award will be made based on responses.

Additional Notes

This RFI/SSN does not commit the Government to any contractual agreement. Proprietary information should be marked. All submissions become Government property and will not be returned. Telephone responses will not be accepted.

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Sources Sought
Posted: Feb 17, 2026
Chemistry Support for the DTT (NIEHS) - RFI/SSN | GovScope