Custom chemical synthesis
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health (NIH), under the Department of Health and Human Services, has issued a Notice of Intent (NOI) to award a Firm-Fixed-Price Purchase Order to Cyclope Bio SL for the custom synthesis of 200 grams of (1S,2S)-trans-N-Boc-1,2-cyclopentanediamine. This chemical is a critical precursor for research into medical diagnostics and treatments for cancer and HIV infection. The place of performance is Llanera, Spain. This is not a request for competitive quotes, but small businesses may submit capability statements. Capability statements are due by June 18, 2026.
Purpose & Overview
This NOI signifies NIH's intention to procure a specialized chemical compound, (1S,2S)-trans-N-Boc-1,2-cyclopentanediamine, which is vital for the synthesis of cyclopentane peptide nucleic acids and their incorporation into thyclotides. These compounds are under investigation for their potential in developing advanced medical diagnostics and therapeutic interventions against cancer and HIV.
Contract Details
- Contract Type: Firm-Fixed-Price Purchase Order
- Intended Awardee: Cyclope Bio SL
- Product/Service Code: 6810 (Chemicals)
- Place of Performance: Llanera, Spain
Set-Aside & Submission
This is not a competitive solicitation. However, interested small businesses, including 8(a), service-disabled veteran owned, HUBZone, small disadvantaged, veteran-owned, and women-owned firms, are invited to submit a written capability statement. This statement should demonstrate their ability to meet the specified requirement. The Government retains discretion to compete the award based on responses received.
Key Deadlines
- Capability Statements Due: No later than 11:00 p.m. EDT on June 18, 2026.
- Award Anticipated: Approximately ten (10) days after the notice date, unless a suitable alternative vendor is identified.
Contact Information
- Primary Contact: David Shen
- Email for Responses: david.shen@nih.gov