DNA and RNA Extraction
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The NATIONAL INSTITUTES OF HEALTH (NIH) has issued a Special Notice for DNA and RNA Extraction services. This notice seeks a vendor capable of performing custom DNA extraction from mouse whole blood (white cell pellets) and custom DNA/RNA extraction from various mouse organs (lung, spleen, heart, kidney, brain, liver), including Agilent RNA QC. The primary objective is to ensure scientific compatibility and avoid batch effects with previously generated datasets. Responses are due March 30, 2026.
Scope of Work
This requirement involves highly specialized laboratory services:
- Custom DNA Extraction: From mouse whole blood (white cell pellets).
- Custom DNA and RNA Extraction: From mouse organs (lung, spleen, heart, kidney, brain, liver), including Agilent RNA Quality Control.
The critical aspect of this work is maintaining consistency in extraction chemistry, instrumentation, workflow, and QC thresholds. Any deviation could introduce batch effects, distort methylation signatures, gene expression profiles, and sequencing quality, rendering new data scientifically incompatible with existing datasets.
Contract & Timeline
- Type: Special Notice
- Product/Service Code: R499 (Other Professional Services)
- Set-Aside: None specified
- Response Due: March 30, 2026, 10:00 AM EDT
- Published: March 23, 2026, 05:42 PM EDT
- Place of Performance: Bethesda, MD, United States
Additional Notes
This notice highlights a critical scientific need to prevent discrepancies that cannot be corrected computationally, which would undermine the validity of combined analyses and jeopardize ongoing studies and submitted manuscripts. Interested parties should demonstrate their capability to meet these stringent consistency requirements.
Contact Information
- Primary Contact: Cifford Lounsbury
- Email: clifford.lounsbury@nih.gov
- Phone: 3014808827