FDA - Intent to Sole Source Molecular Operating Environment
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The U.S. Food and Drug Administration (FDA), specifically the Division of Applied Regulatory Science (DARS), intends to award a sole source contract to Chemical Computing Group ULC for the Molecular Operating Environment (MOE) software. This procurement aims to enhance DARS's analytical capabilities for three-dimensional (3D) structural analysis and representation, which is crucial for evaluating adverse drug reactions that cannot be adequately assessed through 2D approaches alone. Capability statements from other potential sources are due by June 16, 2026.
Scope of Requirement
The requirement is for the Molecular Operating Environment (MOE), a comprehensive cheminformatics and molecular modeling software platform. This software is essential for:
- Conducting robust evaluations of adverse drug reactions.
- Enabling 3D structural analysis and representation.
- Providing customizable molecular docking models.
- Updating computational models with chemical descriptors.
- Supporting chemical database management.
- Modeling diverse types of molecules and molecular interactions (organic, metallic, biomolecules).
Contract & Timeline
- Type: Notice of Intent to Sole Source (not a solicitation)
- Intended Awardee: Chemical Computing Group ULC
- Justification: FAR 6.103-1 (Only one responsible source) due to unique capabilities, licensing agreements, and warranty coverage.
- Period of Performance: A base year (June 29, 2026 - June 28, 2027) plus four one-year option periods, extending through June 28, 2031.
- Set-Aside: None (Sole Source)
- Capability Statement Due: June 16, 2026, by 12:00 PM EST
- Published: June 9, 2026
Additional Notes
This notice is for informational purposes only and is not a solicitation or a request for offers. The Government is not obligated to acknowledge receipt of information or provide feedback. A determination to not compete the procurement is solely at the Government's discretion. Information received will be used to assess the possibility of a competitive procurement.