Future Program: Virtual-Integrated Twin for Autonomous Lifesaving (VITAL)
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO) has issued a Special Notice for the forthcoming Virtual-Integrated Twin for Autonomous Lifesaving (VITAL) program. This notice provides public notification of DARPA's research interests in developing continuously updating computational models of the cardiovascular system to predict outcomes and assess treatment options in real time. This is an informational notice; no proposals or submissions are being accepted at this time.
Scope of Work
The VITAL program aims to establish high-fidelity (HF) digital twins and develop reduced-order models (ROMs) for real-time responsiveness. The vision is to enable future providers and clinicians to assess treatment options for acute and chronic pathologies. The program is structured in two phases:
- Phase 1: Focuses on establishing technical credibility and quantifying HF model performance limits.
- Phase 2: Will evaluate performance tradeoffs associated with HF-to-ROM transitions, including scalability and real-time execution. DARPA encourages teaming to ensure the necessary expertise for this complex effort.
Contract & Timeline
- Type: Special Notice
- Product Service Code: AC12 - National Defense R&D Services; Department Of Defense Military; Applied Research
- Set-Aside: None specified
- Notice End Date: April 10, 2026
- Published: March 3, 2026
Evaluation
This is not a solicitation for proposals or a Request for Information (RFI). DARPA will not accept submissions against this notice. Its purpose is to announce future program interests and planning.
Additional Notes
Interested parties can be added to a blast list for future program updates, including Proposers Day announcements and Program Solicitation publication, by emailing VITAL@darpa.mil. The full solicitation will be made available on sam.gov when released. DARPA also provides a resource called DARPAConnect for those new to doing business with the agency.
Contact: Roozbeh Jafari, PhD, DARPA/BTO Program Manager (VITAL@darpa.mil)