FY2025-2034 DTRA Chemical and Biological Technologies Fundamental Research Broad Agency Announcement

Amendment / Modification

This document is Amendment 4 to the Broad Agency Announcement (BAA) HDTRA1-25-S-0001, "Fundamental Research to Counter Weapons of Mass Destruction (C-WMD)".

Key updates include:

• Topics B1-B6: The pre-application white paper deadline for Topics B1-B6 is March 2, 2026. Papers submitted after this deadline may not be considered.
• Abstract Pre-coordination Waiver: The requirement for abstract pre-coordination is waived for Topics B1-B6. All other pre-coordination requirements remain in effect.

This amendment primarily impacts the "ATTACHMENT 1: SPECIFIC TOPICS" section, specifically detailing the deadlines and pre-coordination requirements for Topics B1-B6.

Potential applicants responding to Topics B1-B6 must adhere to the new pre-application white paper deadline of March 2, 2026. The waiver of abstract pre-coordination for these specific topics simplifies the initial submission process for those topics.

Amendment / Modification

This document is Amendment 3 to the Broad Agency Announcement (BAA) HDTRA1-25-S-0001, titled "Fundamental Research to Counter Weapons of Mass Destruction (C-WMD)".

Key updates include:

• Attachment 1: Specific Topics: Topics B1-B6 are now available. The pre-application white paper deadline for these topics is March 2, 2026. Pre-coordination of abstracts is waived for these specific topics.
• General BAA Information: The BAA is open continuously from October 1, 2024, through September 30, 2034. Submissions to general thrust areas can occur at any time.

This amendment primarily impacts Attachment 1 (Specific Topics) by introducing new topics and their associated deadlines and submission requirements. It also clarifies the overall open period for the BAA and submission procedures for general thrust areas.

Potential applicants should note the new deadline of March 2, 2026, for pre-application white papers related to Topics B1-B6. The waiver of abstract pre-coordination for these specific topics simplifies the initial submission process for those topics.

Amendment / Modification

This document is Amendment 2 to the Broad Agency Announcement (BAA) HDTRA1-25-S-0001, titled "Fundamental Research to Counter Weapons of Mass Destruction (C-WMD)".

• The document indicates that posted amendments supersede all previous versions of the BAA.

• Topics will be listed in Attachment 1 and will be added/closed with Amendments to this BAA.

• Applicants are responsible for monitoring sam.gov and www.grants.gov for posted amendments.

• The original posting date was October 1, 2024.

Amendment / Modification

This document is Amendment 1 to the Broad Agency Announcement (BAA) HDTRA1-25-S-0001, titled "Fundamental Research to Counter Weapons of Mass Destruction (C-WMD)".

• The amendment supersedes all previous versions of the BAA.

• Topics will be listed in Attachment 1 and will be added/closed with Amendments to this BAA.

• The pre-application white paper deadline for Topics A1-A7 is February 7, 2025, by 11:59 PM EST. Papers received after this deadline may not be considered.

• The requirement for abstract pre-coordination is waived for Topics A1-A7.

Solicitation / RFP / RFQ

This Broad Agency Announcement (BAA) from the Defense Threat Reduction Agency (DTRA) solicits proposals for fundamental research to counter Weapons of Mass Destruction (C-WMD). The BAA is intended to identify, adopt, and adapt emerging and revolutionary sciences that can counter C-WMD threats. It covers basic and applied research, as well as educational programs related to C-WMD. Awards are anticipated to be primarily in the form of grants, but cooperative agreements (CAs) or other transactions (OTs) may also be awarded. No contracts will be awarded under this announcement.

• Research proposals are sought for long-term challenges offering significant contributions to knowledge, understanding of phenomena, advancement of technology, new concepts for application, or impact on future C-WMD threat reduction.

• Proposals should address specific topics detailed in Attachment 1 or general thrust areas.

• Pre-application white papers are required for Phase I evaluation, followed by invited proposals for Phase II.

• Research may involve human subjects or animals, requiring specific approvals and adherence to regulations.

• Dual-use research of concern (DURC) will not be funded.

• The BAA is open continuously from October 1, 2024, through September 30, 2034.

• Awards may be for up to five years, with various base and option period structures.

• Grant values can range from $25K up to $1M annually.

• Approximately thirty individual awards are anticipated each year.

• Submissions must be made through www.grants.gov.

• Pre-application white papers require pre-coordination with the appropriate technical point of contact (POC), except where a topic explicitly waives this requirement.

• Evaluation is conducted in two phases: Phase I (pre-application white papers) and Phase II (invited proposals).

• Evaluation criteria include Scientific and Technical Merit, Value to Mission Goals, Capability of Personnel and Facilities, and Cost Realism.

• Key deadlines for Phase I submissions are within 60 days of notification that a white paper is welcomed. Phase II proposal due dates will be provided in the invitation.

• Eligible entities include accredited degree-granting colleges, universities, academic institutions, industrial and commercial entities (including small businesses), not-for-profit entities, and foreign government laboratories.

• Federal academic organizations, federal laboratories, U.S. Government agencies, and certain FFRDCs are excluded from serving as prime awardees but may act as collaborators.

• DTRA encourages proposals demonstrating significant contributions by universities.

• Attachment 1 details specific topics (currently none are listed for Thrust Area 1). Submissions to general thrust areas are welcome.

• Attachment 2 addresses intellectual property considerations, particularly for OTs.

• Applicants must have an active System for Award Management (SAM) registration and a Grants.gov account.