HGMD (Human Gene Mutation Database) MySQL software renewal

SOL #: PCA-NHGRI-00437Pre-SolicitationSole Source

Overview

Buyer

Health And Human Services
National Institutes Of Health
NATIONAL INSTITUTES OF HEALTH OLAO
BETHESDA, MD, 20892, United States

Place of Performance

Bethesda, MD

NAICS

Software Publishers (513210)

PSC

Business Application Off The Shelf Software Delivered By Perpetual License, Which Also Encompasses Enterprise Level Software Enabling Mission Capability And Business Operational Support. (7A21)

Set Aside

No set aside specified

Timeline

1
Posted
Mar 16, 2026
2
Response Deadline
Mar 23, 2026, 3:00 PM

Qualification Details

Fit reasons
  • NAICS alignment with historical contract wins in similar service areas.
  • Scope strongly matches core technical capabilities and delivery model.
Risks
  • Past performance thresholds may require one additional teaming partner.
  • Potential clarification needed on staffing minimums before bid/no-bid.
Next steps

Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.

Quick Summary

The National Institutes of Health (NIH), specifically the NATIONAL INSTITUTES OF HEALTH OLAO, has issued a Presolicitation in the form of a Notice of Intent (NOI) to Sole Source for the renewal of HGMD (Human Gene Mutation Database) MySQL software licenses. The NIH intends to award a Firm-Fixed-Price purchase order to Qiagen, LLC, as they are identified as the only known responsible source. This software is critical for the NIH's exome analysis pipeline. Responses from interested small businesses are due by March 23, 2026, at 11:00 a.m. EST.

Scope of Work

This requirement is for the renewal of HGMD software licenses. The HGMD software is integrated into the NIH's exome analysis pipeline, which is used for determining disease-causing mutations and enabling further experimental analysis. The software provides comprehensive data on human inherited disease mutations, facilitating detailed reports, verification of novel mutations, understanding mutational spectra, analyzing candidate genes, and prioritizing mutations from sequencing data.

Contract & Timeline

  • Contract Type: Firm-Fixed-Price purchase order
  • Product Service Code: 7A21 (Business Application Off The Shelf Software Delivered By Perpetual License)
  • Intended Contractor: Qiagen, LLC (UEI: W2GLKC92ZH73), the manufacturer of the HGMD software.
  • Place of Performance: Bethesda, MD 20892, United States.
  • Published Date: March 16, 2026
  • Response Due: March 23, 2026, by 11:00 a.m. EST
  • Anticipated Award: Approximately five days after the notice date, unless a capable alternative source is identified.

Evaluation

This notice is NOT a request for competitive quotes. However, interested small businesses (including 8(a), service-disabled veteran owned, HUBZone, small disadvantaged, veteran-owned, and women-owned) may submit a written capability statement. The government will review these statements to determine if there is a reasonable expectation of receiving competitive offers, which could lead to a competitive award.

Contact Information

People

Points of Contact

David ShenPRIMARY

Files

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Pre-Solicitation
Posted: Mar 16, 2026
HGMD (Human Gene Mutation Database) MySQL software renewal | GovScope