SOURCES SOUGHT: Acquisition of a Synergy H1 Hybrid Multi-Mode Reader

Statement of Need (SON)

To procure a new multimode plate reader for the Pediatric Oncology Branch (POB), NCI, NIH, to ensure continuity of research, support 10 research programs, and provide a reliable, modern platform. This is to replace an aging instrument that is nearing the end of its support life and represents a single point of failure.

Acquisition of one Agilent BioTek Synergy H1 Hybrid Multi-Mode Reader (Model: H1M Part# SH1M-SN).

• Core Detection Capabilities: Must support absorbance, fluorescence, and luminescence detection in a single instrument, with monochromator-based wavelength selection and full spectral scanning.
• Performance and Sensitivity: High sensitivity for low-signal applications and broad dynamic range.
• Fluorescence Capabilities: Support for top and bottom fluorescence detection and compatibility with modern fluorophores.
• Assay Flexibility: Support for a wide range of assays (ELISA, colorimetric, fluorescent reporter, luminescent viability, gene expression, nucleic acid/protein quantification) and ability to adjust excitation/emission wavelengths.
• Modularity and Future Expansion: Modular design for future upgrades (e.g., TRF or FP detection).
• Plate and Sample Compatibility: Accommodate standard microplate formats (6- to 384-well) and support microvolume sample analysis.
• Environmental and Operational Features: Temperature control, incubation capabilities, orbital shaking, and compatibility with automated workflows and laboratory software.
• Service and Support: Ongoing manufacturer support, service availability, and access to software updates and technical support.
• Physical and Space Requirements: Compact benchtop footprint compatible with existing laboratory space.

Item shall be delivered within 60 days of purchase order award.

This is a Firm Fixed-Price Purchase Order.

Notice of Intent to Sole Source

This document is a Notice of Intent to award a Firm-Fixed-Price Purchase Order to Agilent Technologies Inc. for maintenance services for the Agilent Seahorse XFe96 Analyzer (SN: US411504). The National Institutes of Health (NIH) has identified Agilent Technologies Inc. as the only responsible source capable of providing these services, citing FAR Part 6.302-1.

The service contract includes:

• Repairs, software updates, and preventative maintenance (PM).

• Unlimited phone and email support.

• 100% on-site visits with labor and parts for any repairs.

• One PM visit per year (on request).

• Software upgrades and new features/enhancements.

• Two application scientist visits for applications updates.

• Instrument recertification every 12 months.

• The contract type is Firm-Fixed-Price.

• The period of performance is anticipated to be 12 months, with renewal expected annually.

• The projected cost is less than the previous contract's total cost.

This is not a request for competitive quotes. However, interested small businesses (8(a), service-disabled veteran owned small business, HUBZone, small disadvantaged business, veteran-owned small business, and women-owned small business) may submit a written capability statement demonstrating their ability to perform the requirement.

While this is a sole source notice, small businesses are invited to submit capability statements.

• The Seahorse XFe96 Analyzer is critical for Urologic Oncology Branch (UOB) research on hereditary urologic cancer.
• Agilent Technologies Inc. is the manufacturer and sole distributor, making them the only entity capable of servicing or repairing the product.
• Responses to this notice should be emailed to david.shen@nih.gov no later than 7:00 a.m. EST on April 15, 2026.
• An award is anticipated approximately five (5) days after the notice date, contingent on the Government's determination regarding other potential vendors.