Nanopore Sequencing
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health (NIH) Office of Acquisition and Logistics Management (OALM), on behalf of the National Institute of Environmental Health Sciences (NIEHS), intends to award a non-competitive purchase order for Nanopore Sequencing to Alamya Health, OPBC (United States). This acquisition is a Request for Quotation (RFQ) under FAR Part 13 (Simplified Acquisition Procedures) and FAR Part 12 (Acquisition of Commercial Items). Responses are due March 16, 2026.
Scope of Work
The contractor will provide services for profiling DNA methylation alterations in 20 cell lines (10 affected by Bosma arhinia microphthalmia syndrome (BAMS) and 10 control cell lines). This includes:
- HMW gDNA extraction (cell pellets) and blue pippin size selection
- PacBio genomic library construction
- Revio sequencing
- Bioinformatic analysis and data storage
- Deposition of data in the European Genome Archive (EGA)
Contract Details
- Notice Type: Combined Synopsis/Solicitation (Non-Competitive Intent)
- Solicitation Number: 75N94026Q00054
- NAICS Code: 541380 (Small Business Size Standard: $19M)
- Set-Aside: None
- Period of Performance: Approximately 12 weeks, determined at award
- Place of Performance: National Institute of Environmental Health Sciences (NIEHS), Durham, NC
- Anticipated Award Date: March 18, 2026
Non-Competitive Justification
This is a sole source acquisition based on the need to maintain scientific continuity for an ongoing study. Alamya Health has previously provided these services to NIEHS, and introducing unknown variables could invalidate prior research data.
Submission Requirements
Offerors must submit clear and convincing evidence of their capability to fulfill the requirement, including a price proposal detailing labor categories, estimated hours, fully loaded fixed hourly rates, and a breakdown of other direct costs. Responses must also include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and certification of business size. All offerors must have an active registration in SAM.gov.
Key Attachments & Clauses
- FAR 52.204-24: Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment
- FAR 52.204-26: Covered Telecommunications Equipment or Services
- Invoice and Payment Provisions (HHSAR 352.222-70, NIH Invoice and Payment Instructions)
Deadlines & Contact
- Responses Due: March 16, 2026, 9:00 am Eastern Standard Time
- Submission: Electronically to Sarah Bank (sarah.bank@nih.gov)
- Contact: Sarah Bank, Contracting Officer (sarah.bank@nih.gov)