NGS services to support clinical research
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, is seeking proposals for Next Generation Sequencing (NGS) services to support clinical and research activities related to bone marrow failure syndromes. This is a Total Small Business Set-Aside for a firm-fixed-price purchase order. Proposals are due May 29, 2026, at 9:00 AM EDT.
Scope of Work
The awarded contractor will perform genomic sequencing on patient-derived samples (peripheral blood, bone marrow, plasma, or FFPE tissue) to detect somatic and germline mutations relevant to hematologic conditions. Key requirements include:
- Utilizing a sequencing panel covering approximately 300+ genes associated with hematologic malignancies and bone marrow failure syndromes, including UBA1 (VEXAS syndrome), TERT, and GATA2.
- Detecting point mutations, insertions/deletions, and relevant structural variants.
- Processing multiple specimen types.
- Providing results via a secure electronic portal within 10 calendar days of sample receipt.
- Employing a standardized methodology for consistency and reproducibility.
Contract & Timeline
- Contract Type: Firm-Fixed-Price Purchase Order
- Period of Performance: June 1, 2026, to May 31, 2027
- Set-Aside: Total Small Business Set-Aside (FAR 19.5)
- NAICS Code: 621511 – Medical Laboratories (Small Business Size Standard: $41.5 million)
- Solicitation Number: 75N98026Q00369
- Proposal Due: May 29, 2026, at 9:00 AM EDT
- Published: May 15, 2026
Submission & Evaluation
Proposals must be submitted electronically to nicholas.capobianco@nih.gov. Required information includes unit and total price, shipping/handling costs, delivery timeframe, delivery terms, F.O.B. point, product/service description, Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. Offerors must be registered in SAM.gov and include a completed FAR 52.212-3. Evaluation factors are Technical Capability (most important), Past Performance, and Price. Technical capability and past performance are more important than price.
Additional Notes
This acquisition is conducted under FAR Subpart 12.6 for streamlined solicitation of commercial items and is not expected to exceed the simplified acquisition threshold. Demonstrated experience supporting longitudinal clinical research studies is preferred.