NOI - Dynamic Genome: CHIP
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a firm-fixed-price purchase order to Vanderbilt University Medical Center for specialized computational analysis services. This is a non-competitive Notice of Intent (NOI) to identify clonal hematopoiesis of indeterminate potential (CHIP) in longitudinal whole genome sequencing datasets. This effort is a follow-on to prior work, crucial for maintaining methodological consistency and reproducibility. Responses from interested parties are due May 29, 2026, at 9:00 AM EDT.
Scope of Work
The contractor will provide specialized computational analysis services, including:
- Performing longitudinal analysis of Whole Genome Sequencing (WGS) data from the Framingham Heart Study across two timepoints (over 10 years apart).
- Recalibrating prior datasets.
- Detecting somatic mutations.
- Identifying clonal hematopoiesis of indeterminate potential (CHIP) using validated analytical pipelines. Services will be performed at the contractor's facility, with data accessed remotely via dbGaP and the TOPMed Data Exchange.
Contract & Timeline
- Type: Firm-fixed-price purchase order
- Period of Performance: June 1, 2026, to September 30, 2026
- Set-Aside: None (no set-aside restrictions)
- Response Due: May 29, 2026, at 9:00 AM EDT
- Published: May 15, 2026
Submission & Evaluation
This announcement serves as the only solicitation; a separate written solicitation will not be issued. Interested parties may submit a capability statement demonstrating their ability to meet the requirement. Responses must include:
- Sufficient information to establish bona-fide capabilities.
- Unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point, product or catalog number(s), product description, and other relevant factors (e.g., past performance, special features, warranty).
- A completed copy of FAR clause 52.212-3, Offeror Representations and Certifications—Commercial Items. All offerors must have an active registration in the System for Award Management (SAM).
Additional Notes
This acquisition is conducted under the authority of FAR Part 12.603 (Streamlined solicitation for commercial products or services) and 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii). The NAICS Code is 541990 (All Other Professional, Scientific and Technical Services) with a small business size standard of $19.5M. The solicitation number is 75N98026Q00362. Responses should be submitted electronically to nicholas.capobianco@nih.gov.