Notice of Intent to Sole Source - Mouse Colony Breeding Service
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Heart, Lung, and Blood Institute (NHLBI) intends to award a Firm Fixed-Price purchase order on a sole source basis to Ozgene (Bentley, WA, Australia) for Mouse Colony Breeding Services. This acquisition aims to provide specialized mouse models carrying the human δ-globin gene, essential for evaluating the impact of the KLF1–GATA1 fusion protein and candidate compounds on SCD and β-thalassemia phenotypes. Responses from interested parties are due March 26, 2026, at 9 A.M. Eastern Daylight Time (EDT).
Scope of Work
The required services include:
- Breeding and maintenance of transgenic HBB, HBBS, and HBBE knock-in mouse lines.
- Crossing these lines with the Townes mouse model to generate fully humanized mice, with or without specific mutations.
- Specific deliverables include: 5 HBA/HBA, HBB(Dash)/HBB(Dash) males and females (6-8 weeks old), and 5 HBA/HBA, HBB(Mirage)/HBB(Mirage) males and females (6-8 weeks old).
Contract Details
- Type: Firm Fixed-Price Purchase Order (Pre-solicitation Non-Competitive)
- Estimated Value: Not exceeding $7 million
- Period of Performance: 12-15 months, commencing June 1, 2026, and concluding May 31, 2027.
- Place of Performance: Ozgene, Bentley, WA 6102, Australia.
- Acquisition Authority: Conducted under FAR subpart 13.5 (Simplified Procedures for Certain Commercial Items) and FAR subpart 12 (Acquisition of Commercial Items).
- Set-Aside: This acquisition is not set aside for small businesses.
- NAICS Code: 112990 - All Other Animal Production ($2.75 Million SBA Size Standard).
Submission & Evaluation
- This is a Notice of Intent to Sole Source to Ozgene and is not a request for competitive proposals. However, interested parties may identify their interest and capability to challenge the sole source determination.
- Responses should include: unit price, list price, shipping and handling costs, delivery period after contract award, prompt payment discount terms, F.O.B. Point, Unique Entity Identifier (UEI), and Taxpayer Identification Number (TIN).
- All offerors must have an active registration in the System for Award Management (SAM).
- Responses are due: March 26, 2026, at 9 A.M. Eastern Daylight Time (EDT).
- Submission: Electronically to Nicholas Capobianco at nicholas.capobianco@nih.gov.
Additional Notes
The government has determined Ozgene is the only responsible source due to the necessity of maintaining an established breeding colony and to avoid duplication of cost, delays, and scientific risks associated with transferring the work. The Solicitation Number is PCA-NHLBI-01737.