Notice to Intent to Sole Source - Bio-Plex Reagents
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health, Clinical Center (NIH-CC) has issued a Notice of Intent to Sole Source for Bio-Plex Reagents from Bio-Rad Laboratories. This acquisition is for Bio-Plex Pro Human Cytokine Screening Panel, 48-Plex kits, Bio-Plex Calibration kit, and Validation kit, essential for clinical CAR-T potency testing. Capability statements from responsible sources are due by February 14, 2026, 12:00 PM EST.
Scope of Work
The NIH-CC, Center for Cellular Engineering (CCE), requires these Bio-Plex products for CAR-T cell potency testing throughout the development and manufacturing of CAR-T cells. Key features and benefits of the Bio-Plex Pro Human Cytokine Screening Panel, 48-Plex, calibration, and validation kits include:
- Designed for quantification of a panel of 48 cytokines, chemokines, and growth factors.
- Usable with various sample types, including serum, plasma, and culture supernatant.
- Compiles profiles of a series of cytokine and chemokine markers, providing more data from each sample.
- Highly suitable for researchers seeking predictive biomarkers using small sample volumes (12.5ul per well).
- Assays can be run in a significantly shorter time (~2 hours) compared to conventional ELISA techniques.
- Ready-to-use validation and calibration kits with unique individual vials of each reagent.
Contract & Timeline
- Type: Special Notice (Notice of Intent to Sole Source)
- Vendor: Bio-Rad Laboratories
- Duration: Three months (May 1, 2026 - August 1, 2026)
- Set-Aside: None (Sole Source)
- Response Due: February 14, 2026, 12:00 PM EST
- Published: February 4, 2026
- Place of Performance: Bethesda, MD
Evaluation
This is not a Request for Proposal. The government intends to negotiate on an other than full and open competition basis with Bio-Rad Laboratories, citing 41 U.S.C. 1901 (a) (1) as implemented by FAR 13.106-1 (only one responsible source). All responsible sources that could provide the required items may submit a capability statement for consideration. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.
Additional Notes
Submissions should be sent via email to valerie.gregorio@nih.gov with the subject line "NOI-CC-26-002244".