Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit)

SOL #: DARPA-PS-26-28Solicitation

Overview

Buyer

DEPT OF DEFENSE
Defense Advanced Research Projects Agency (Darpa)
DEF ADVANCED RESEARCH PROJECTS AGCY
ARLINGTON, VA, 222032114, United States

Place of Performance

Place of performance not available

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

PSC

National Defense R&D Services; Department Of Defense Military; Applied Research (AC12)

Set Aside

No set aside specified

Timeline

1
Posted
May 1, 2026
2
Submission Deadline
May 20, 2026, 5:00 PM

Qualification Details

Fit reasons
  • NAICS alignment with historical contract wins in similar service areas.
  • Scope strongly matches core technical capabilities and delivery model.
Risks
  • Past performance thresholds may require one additional teaming partner.
  • Potential clarification needed on staffing minimums before bid/no-bid.
Next steps

Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.

Quick Summary

The Defense Advanced Research Projects Agency (DARPA), specifically the Biological Technologies Office (BTO), has issued a Solicitation (DARPA-PS-26-28) for the Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit) program. This initiative seeks to develop integrated biological processing units (BPUs) to address power inefficiencies in advanced AI/ML applications for Department of War (DoW) edge operations. The program aims to improve learning, inference, and computational memory in neural tissue systems, ultimately for drone navigation tasks using odorant detection. Abstracts are due May 20, 2026, by 5:00 PM ET.

Scope of Work

The O-Circuit program is structured into two primary task areas:

  • Task Area 1 (TA1): Architecture: Focuses on developing novel BPUs with advanced learning and memory capabilities, including complex BPU architectures (e.g., organoids, assembloids) and enhancing synaptic connectivity and plasticity.
  • Task Area 2 (TA2): Action: Involves integrating BPUs with biologically based odorant sensing systems and drone navigation platforms to create a Sense-Compute-Action system capable of detecting and responding to odorants for drone control.

Contract & Timeline

  • Contract Type: Other Transaction (OT) for Prototype agreements.
  • Anticipated Awards: Approximately five to seven awards.
  • Total Value: $36M for Phase 1 and Phase 2.
  • Period of Performance: 32 months (18 months for Phase 1, 14 months for Phase 2).
  • Published Date: May 1, 2026.
  • Abstracts Due Date: May 20, 2026, 5:00 PM ET.
  • Questions Due Date: May 7, 2026, 5:00 PM ET.
  • Proposer Workshop: April 10, 2026.

Submission & Evaluation

This is a two-stage acquisition process. Proposers must first submit an abstract using the mandatory template (DARPA-PS-26-28-Attachment_B-Abstract_Template.docx). Abstracts will be reviewed for technical comprehension and ability. Selected proposers will then be invited to submit Oral Proposal Packages (OPPs) and participate in oral presentations. Failure to submit an abstract and receive an invitation will result in the OPP not being reviewed.

Eligibility / Set-Aside

Solutions are encouraged from all responsible sources, including large and small businesses, nontraditional defense contractors, and research institutions. No specific set-aside is designated.

Additional Notes

Attachments include an Abstract Summary Slide Template, the mandatory Abstract Template, and a Model Other Transaction (OT) Streamlined, Fixed form, which provides insight into the contractual framework. The primary contact is Dr. Jeffrey Zaleski, Program Manager, DARPA/BTO, at O-circuit@darpa.mil.

People

Points of Contact

Dr. Jeffrey Zaleski, Program Manager, DARPA/BTOPRIMARY

Files

Files

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Versions

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Solicitation
Posted: May 1, 2026
Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit) | GovScope