Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit)
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Defense Advanced Research Projects Agency (DARPA), specifically the Biological Technologies Office (BTO), has issued a Solicitation (DARPA-PS-26-28) for the Organoid Cytomorphic Intelligence Resulting from Convergent Understanding and Information Transfer (O-Circuit) program. This initiative seeks to develop integrated biological processing units (BPUs) to address power inefficiencies in advanced AI/ML applications for Department of War (DoW) edge operations. The program aims to improve learning, inference, and computational memory in neural tissue systems, ultimately for drone navigation tasks using odorant detection. Abstracts are due May 20, 2026, by 5:00 PM ET.
Scope of Work
The O-Circuit program is structured into two primary task areas:
- Task Area 1 (TA1): Architecture: Focuses on developing novel BPUs with advanced learning and memory capabilities, including complex BPU architectures (e.g., organoids, assembloids) and enhancing synaptic connectivity and plasticity.
- Task Area 2 (TA2): Action: Involves integrating BPUs with biologically based odorant sensing systems and drone navigation platforms to create a Sense-Compute-Action system capable of detecting and responding to odorants for drone control.
Contract & Timeline
- Contract Type: Other Transaction (OT) for Prototype agreements.
- Anticipated Awards: Approximately five to seven awards.
- Total Value: $36M for Phase 1 and Phase 2.
- Period of Performance: 32 months (18 months for Phase 1, 14 months for Phase 2).
- Published Date: May 1, 2026.
- Abstracts Due Date: May 20, 2026, 5:00 PM ET.
- Questions Due Date: May 7, 2026, 5:00 PM ET.
- Proposer Workshop: April 10, 2026.
Submission & Evaluation
This is a two-stage acquisition process. Proposers must first submit an abstract using the mandatory template (DARPA-PS-26-28-Attachment_B-Abstract_Template.docx). Abstracts will be reviewed for technical comprehension and ability. Selected proposers will then be invited to submit Oral Proposal Packages (OPPs) and participate in oral presentations. Failure to submit an abstract and receive an invitation will result in the OPP not being reviewed.
Eligibility / Set-Aside
Solutions are encouraged from all responsible sources, including large and small businesses, nontraditional defense contractors, and research institutions. No specific set-aside is designated.
Additional Notes
Attachments include an Abstract Summary Slide Template, the mandatory Abstract Template, and a Model Other Transaction (OT) Streamlined, Fixed form, which provides insight into the contractual framework. The primary contact is Dr. Jeffrey Zaleski, Program Manager, DARPA/BTO, at O-circuit@darpa.mil.