ORNL-TT-2026-02
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The U.S. Department of Energy (DOE), through UT-Battelle, LLC at Oak Ridge National Laboratory (ORNL), is seeking commercialization partners for its patent-pending technology: "Methods for Immunoregulation by Modulating Plasminogen-Apple-Nematode (PAN) Domain-Containing Proteins." The ORNL Technology Transfer Office will accept license applications through April 27, 2026.
Scope of Technology
This opportunity focuses on technology 4200 – A PROTEIN DOMAIN MODULATING HOST-CELL INVASION. The invention demonstrates that a fully functional protein domain can suppress host immunity, facilitating host-cell invasion by symbionts, pathogens, and parasites across eukaryotic organisms. Specific modifications to essential amino acids within this domain can induce defense responses to prevent host-cell invasion. This technology can be engineered to either facilitate or prevent host-cell invasion by various organisms, including bacteria, fungi, nematodes, Rickettsia, and Plasmodium sp.
Applications and Industries
- Healthcare
- Biology
Opportunity Details & Timeline
- Type: Special Notice (Technology Transfer/Licensing)
- Agency: Department of Energy / ORNL UT-Battelle LLC
- Response Due: April 27, 2026, 5:00 PM ET
- Published: March 13, 2026
- Set-Aside: None specified (Technology Transfer)
Contact Information
For inquiries, please contact:
- Primary: Leslie Smith (smithlm@ornl.gov)
- Secondary: Sue Burchfield (burchfieldse@ornl.gov)