PAXGENE Ribonucleic acid extraction, quality control and aliquoting services
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health (NIH), specifically the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), has issued a Presolicitation for PAXgene Ribonucleic acid (RNA) extraction, quality control, and aliquoting services. These services are required to support ongoing NIDDK clinical protocol research and downstream transcriptomic analysis. Responses are due by June 20, 2026.
Scope of Work
The objective is to procure services for RNA extraction, quantitation, normalization, Agilent quality control, and aliquoting for samples collected from 50 clinical participants. The contractor shall provide services for 122 PAXgene tube units, including:
- High-quality RNA extraction from PAXgene tubes using validated protocols.
- RNA quantitation and normalization for consistent sample concentrations.
- Deoxyribonuclease (DNase) treatment to remove genomic DNA contaminants.
- RNA integrity and quality assessments using Agilent instrumentation.
- Aliquoting up to twenty-one (21) aliquots per sample.
- Secure frozen storage conditions to prevent sample degradation.
- Shipment of samples on dry ice.
- Maintenance of complete documentation and traceability records.
Quality Control & Repository Management
- All specimens must meet the contractor’s established quality control acceptance criteria upon receipt.
- The contractor must inspect specimens and immediately notify NIDDK of any compromised or nonconforming samples.
- Specimen integrity verification includes visual inspection and temperature monitoring.
- The contractor shall provide certificates of analysis, donor documentation, shipping documentation, and chain-of-custody records.
- Specimens must be maintained and stored under appropriate frozen conditions.
- Order status updates and shipment tracking information must be provided to NIDDK personnel.
Contract & Timeline
- Type: Presolicitation
- Product/Service Code: R499 (Other Professional Services)
- Set-Aside: None specified
- Response Due: June 20, 2026, 1:00 PM EDT
- Published: June 10, 2026, 2:26 PM EDT
- Place of Performance: Maryland (20892), United States
Contact Information
- Primary Point of Contact: John Burton, burtonjo@mail.nih.gov