Quadrupole-Orbitrap Hybrid Mass Spectrometer
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Food and Drug Administration (FDA), Human Foods Program (HFP), is conducting market research via a Sources Sought notice to identify small business concerns capable of providing a quadrupole-orbitrap hybrid mass spectrometer system. This system is required for the Division of Analytical Chemistry, Spectroscopy Mass Spectrometry Branch, located in College Park, MD. The purpose is to support qualitative and quantitative proteomic research methods for analyzing complex protein mixtures in FDA-regulated foods and human cell samples. Responses are due by April 27, 2026, at 10:00 AM Eastern Time.
Purpose & Scope
The HFP requires this advanced mass spectrometer to develop critical proteomic research methods. These methods will aid in assessing toxicological effects and developing New Approach Methods (NAMs) by analyzing complex protein mixtures with high mass resolution, increased sensitivity, and high scan speeds. The system must offer operational flexibility across various acquisition modes (e.g., DDA, DIA, PRM).
Key Requirements / Deliverables
The vendor must supply a newly manufactured quadrupole-orbitrap hybrid mass spectrometer system, including:
- Ion source housing, independent syringe pump, vacuum system, and high-capacity transfer tube.
- Resolving injection filter, bent trap, segmented quadrupole mass filter, and high-field orbitrap mass analyzer.
- Integrated computer-based data system with analysis software.
- Maintenance Consumables Kit and a 12-month factory warranty with standard preventive maintenance.
- Option for an uninterruptable power supply (UPS). Services include:
- Shipping, delivery, installation, integration, and system setup at the FDA laboratory in College Park, MD.
- System testing, calibration, and performance demonstration.
- A one-year service contract (parts, labor, PM, technical support) after installation.
- Three-day on-site, instructor-led training for FDA users.
- Trade-in service and deinstallation of existing instrumentation. Delivery is required prior to September 30, 2026.
Submission Details
Interested small business concerns should submit a Capability Statement electronically to Freshta.Javid@fda.hhs.gov. The subject line must be "Sources Sought – Quadrupole-Orbitrap Hybrid Mass Spectrometer– HFP-2026-132840". Responses are limited to 10 pages (excluding cover page and attachments) in PDF or Word format. The capability statement should indicate if the company can perform at least 51% of the work under a small business set-aside.
Contract & Timeline
- Opportunity Type: Sources Sought (Market Research)
- NAICS Code: 334516 — Analytical Laboratory Instrument Manufacturing (Small Business Size Standard: 1,000 employees)
- PSC: 6640 — Laboratory Equipment And Supplies
- Response Due: April 27, 2026, 10:00 AM ET
- Published Date: April 20, 2026
- Delivery Required By: September 30, 2026
Eligibility / Set-Aside
This is specifically for small business concerns. Respondents should confirm their ability to perform at least 51% of the work if this were to become a small business set-aside.
Additional Notes
This notice is solely for market research and planning purposes and does not constitute a solicitation (RFP, IFB, or RFQ). The government will not reimburse respondents for costs incurred.