Rapid Assessment Machine Learning Software License
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The U.S. Food and Drug Administration (FDA), specifically the Center for Tobacco Products (CTP), is soliciting proposals for Rapid Assessment Machine Learning Software Licenses (ADMET Predictor or equal). This is a Firm Fixed Price (FFP) contract to support toxicology data mining and assessment of chemicals in tobacco products. Proposals are due February 17, 2026, at 3:00 PM ET.
Purpose & Overview
The Government's objective is to obtain brand name or equal ADMET Predictor software licenses for the CTP/OS/Division of Nonclinical Sciences. The software will be utilized by CTP personnel for toxicology data mining and assessing the potential toxicity of chemicals in tobacco products, particularly those with limited or no existing toxicology data.
Key Requirements / Deliverables
- Renewal of eight (8) ADMET Predictor software licenses, covering modules such as Physicochemical and Biopharmaceutical, MedChem Designer, Chemistry, Toxicity, Metabolism, HTPK Simulation, ADMET Modeler, and MedChem Studio.
- Provision of software updates and ongoing maintenance.
- Delivery of continuous training and technical support (via telephone, web-based, or email).
- The software must perform various chemoinformatics functions, including physicochemical property prediction, pharmacokinetic parameter prediction, metabolism prediction, and mutagenicity prediction.
- Compatibility with existing ADMET Predictor models and the FDA environment is essential.
- The software must enable users to create custom models and conduct structure-activity relationship (SAR) evaluations.
- Compliance with Section 508 accessibility standards is required.
Contract Details
- Contract Type: Firm Fixed Price (FFP) purchase order.
- Period of Performance: A base period from February 20, 2026, to February 19, 2027, with four (4) one-year option periods, not to exceed a total duration of 5 years.
- NAICS Code: 513210 (Software Publishers).
- PSC Code: 7A21 (Business Application Off The Shelf Software Delivered By Perpetual License).
- Set-Aside: None specified.
Submission & Evaluation
- RFQ Issuance Date: February 10, 2026.
- RFQ Close Date: February 17, 2026, 3:00 PM Eastern Time.
- Questions Due: February 12, 2026, 10:00 AM ET. Submit questions to Robert Waite (robert.waite@fda.hhs.gov) with a copy to Narissa Charles (Narissa.Charles@fda.hhs.gov).
- Evaluation Factors: Award will be based on the Lowest Price Technically Acceptable (LPTA) methodology, considering total price and technical features meeting requirements.
Additional Notes
This is a combined synopsis/solicitation issued under FAR Part 12 and Subpart 13.2 procedures. The government reserves the right to not respond to questions received after the deadline. Applicable FAR and HHSAR provisions and clauses are those in effect through Federal Acquisition Circular 2025-06.