Restorative and health-Enhancing Sleep Time (REST)

SOL #: ARPA-H-SOL-26-159Solicitation

Overview

Buyer

Health And Human Services
National Institutes Of Health
ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Washington, DC, 20005, United States

Place of Performance

Place of performance not available

NAICS

Research and Development in the Physical (541715)

PSC

Health R&D Services; Health Care Services; Experimental Development (AN13)

Set Aside

No set aside specified

Timeline

1
Posted
Jun 16, 2026
2
Last Updated
Jun 16, 2026
3
Submission Deadline
Aug 12, 2026, 4:00 PM

Qualification Details

Fit reasons
  • NAICS alignment with historical contract wins in similar service areas.
  • Scope strongly matches core technical capabilities and delivery model.
Risks
  • Past performance thresholds may require one additional teaming partner.
  • Potential clarification needed on staffing minimums before bid/no-bid.
Next steps

Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.

Quick Summary

The Advanced Research Projects Agency for Health (ARPA-H) seeks proposals for the Restorative and health-Enhancing Sleep Time (REST) program. This initiative aims to transform how poor sleep is measured and treated by developing objective, home-based, closed-loop technologies. The program focuses on detecting health-relevant sleep microstructures and responding in real time to improve long-term health outcomes. Solution Summaries are due August 12, 2026, at 12pm ET.

Purpose & Scope

The REST program, under ARPA-H's Proactive Health Office (PHO), seeks to establish a technical foundation for a new generation of objective, personalized sleep health technologies. It addresses the significant public health and economic burden of poor sleep.

Proposals are sought for two Technical Areas (TAs):

  • TA1: Measure & Diagnose: Develop validated, in-home systems for objective sleep physiology measurement, diagnosis of poor sleep (insomnia-focused), and classification of mechanistic sleep subtypes. This includes hardware/software, clinic-to-home translation, and integration.
  • TA2: Control & Treat: Develop noninvasive, closed-loop systems that use real-time physiological measurements to personalize and deliver interventions during sleep to improve sleep quality and treat insomnia. This involves real-time neuromodulation, multi-microstructure targeting, and regulatory/commercialization readiness.

Shared non-solicited program resources (Foundational Sleep Health Modeling, Research Integrator, IV&V) will also be available.

Contract Details

  • Award Instrument: Other Transaction (OT) agreements.
  • Period of Performance: 66 months (5.5 years), structured into three phases: Prove Core Technical Thesis (24 mos), Demonstrate Proof-of-Concept (18 mos), and Clinical Translation and Commercialization Preparation (24 mos).

Submission & Evaluation

  • Solution Summary Submission Deadline: August 12, 2026, at 12pm ET. Proposers must use the provided template (Attachment A).
  • Full Proposal: Invited proposers will submit written materials and an in-person pitch.
  • Evaluation Criteria: Scientific and technical merit, feasibility, innovation, proposer capabilities, and relevant experience. Budget reasonableness will be assessed for full proposals.

Eligibility

  • ARPA-H welcomes proposals from commercial performers, academic institutions, and non-profit organizations.
  • Federally Funded Research and Development Centers (FFRDCs) and government entities are not permitted as prime or sub-performers.
  • Awards will prioritize entities conducting work in the United States.
  • Active SAM.gov registration and Unique Entity Identifier (UEI) are required.

Key Dates & Notes

  • Proposer's Day: July 13, 2026.
  • Industry cost share is encouraged, particularly in later phases (10% in Phase 2, 50% in Phase 3 for TA1).
  • Out-of-scope activities include general wellness tracking, solely pharmacologic treatment, or non-personalized interventions.
  • Contact: rest@arpa-h.gov.

People

Points of Contact

REST TeamPRIMARY

Files

Files

No files attached to this opportunity

Versions

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Posted: Jun 16, 2026
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Posted: Jun 16, 2026