Smart Red Blood Cells (Smart-RBC)
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals in support of the Smart Red Blood Cells program (Smart-RBC). The DARPA Smart-RBC program aims to engineer red blood cells to contain novel biological features that can safely, temporarily, and reliably alter human physiology. Specifically, the Smart-RBC program will revolutionize blood products by creating “smart red blood cells” (SRBCs). SRBCs will be engineered to contain additional biological circuits consisting of three layers: Sense extracellular biomarkers; Decide next steps; Act by creating effector molecules that can alter metabolism or physiology. The program will identify the art-of-the-possible to create SRBCs to enhance human performance and maximize survival via hemostasis products. This program does not include clinical trials or direct human testing.