Two-photon Mesoscale Imaging System with Holographic Stimulation Capability
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The National Institutes of Health (NIH), under the Department of Health and Human Services, has issued a Presolicitation Notice (Notice of Intent to Sole Source) for a Two-photon Mesoscale Imaging System with Holographic Stimulation Capability. The NIH intends to award a contract to Pacific Optica (University of California, Santa Barbara) without full and open competition. However, interested parties may submit capability statements. Responses are due May 8, 2026, at 9:00 AM Eastern Time.
Scope of Work
The NIH requires an advanced imaging system to monitor small numbers of cells in awake and behaving animals. The "Dual Independent Enhanced Scan Engine for Large field-of-view Two-Photon imaging (Diesel2p)" platform is sought for its improved imaging access, subcellular resolution over a large field-of-view, and crucial holographic 2P stimulation capability for optogenetic research.
Contract & Timeline
- Type: Presolicitation / Notice of Intent to Sole Source
- Set-Aside: None (intended non-competitive award)
- Product Service Code: 6640 (Laboratory Equipment And Supplies)
- NAICS: 334516
- Response Due: May 8, 2026, 9:00 AM ET
- Published: April 28, 2026
- Place of Performance: Bethesda, MD
Submission & Evaluation
This is not a request for competitive proposals. However, the government will consider responses from other interested parties to determine if a competitive procurement is warranted. Submissions must include a technical proposal, cost-price proposal, period of performance, Unique Entity ID (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in SAM. This acquisition is conducted under FAR Part 13 (Simplified Acquisition Procedures) and is not expected to exceed the simplified acquisition threshold ($350,000).
Contact Information
Submit responses electronically to Michael Falzone, Contracting Officer, at Michael.falzone@nih.gov. Reference solicitation number 75N98026Q00275.