Xemistry software
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Department of Health and Human Services (HHS), specifically the Program Support Center Acquisition Management Services, is issuing a Request for Quotation (RFQ) for the renewal of Xemistry software, which includes the CACTVS Chemoinformatics Toolkit. This is an unrestricted acquisition for a firm-fixed-price contract. Quotes are due April 10, 2026, at 11:00 am Eastern Time.
Scope of Work
This opportunity seeks the renewal of the CACTVS Chemoinformatics Toolkit, a brand-name product from Xemistry GMBH. The software is utilized by PubChem developers for its powerful general-purpose chemical information processing capabilities and unique multi-threading features. A Brand Name Justification indicates that Xemistry GMBH is the sole proprietor and technical support provider for this toolkit, potentially limiting competition.
Contract & Timeline
- Type: Firm-Fixed-Price Request for Quotation (RFQ)
- Set-Aside: Unrestricted (Full and Open Competition)
- NAICS Code: 541519 (Other Computer Related Services)
- Product/Service Code: 7A21 (IT AND TELECOM BUSINESS APPLICATION SOFTWARE LICENSE - PERPETUAL SOFTWARE)
- Period of Performance:
- Base Year: April 14, 2026 – April 13, 2027
- Option Period 1: April 14, 2027 – April 13, 2028
- Option Period 2: April 14, 2028 – April 13, 2029
- Questions Due: April 9, 2026, 10:00 am Eastern Time
- Quotes Due: April 10, 2026, 11:00 am Eastern Time
- Published: April 8, 2026
Evaluation
Award will be made using the Lowest Priced Technically Acceptable (LPTA) procedure. Offerors must provide the specified products/services and submit a firm-fixed-price quote. Open market pricing is accepted. Offerors must be authorized resellers of the specified products.
Submission & Contact
All questions and quotes must be submitted via email.
- Questions Email: EmRia.Briscoe@hhs.gov and Kwasi.Antwi@hhs.gov (Subject: “Xemistry Software Renewal – Solicitation 75N98026Q00169”)
- Quote Email: EmRia.Briscoe@hhs.gov and Kwasi.Antwi@hhs.gov (Subject: “Xemistry Software Renewal – Solicitation 75N98026Q00169”)
- Primary Contact: Em'Ria Briscoe (EmRia.Briscoe@hhs.gov)
- Secondary Contact: Kwasi Antwi (Kwasi.Antwi@hhs.gov)