Q--NGS services to support clinical research

Solicitation / RFP / RFQ

This is a combined synopsis/solicitation for commercial items to procure Next Generation Sequencing (NGS) services. The National Institutes of Health (NIH) seeks to award a firm-fixed-price purchase order for services supporting clinical and research activities related to bone marrow failure syndromes, including aplastic anemia and related disorders.

• Perform genomic sequencing on patient-derived samples (peripheral blood, bone marrow, plasma, or FFPE tissue).

• Detect somatic and germline mutations relevant to hematologic conditions.

• Utilize a sequencing panel covering approximately 300+ genes associated with hematologic malignancies and bone marrow failure syndromes, including specific genes like UBA1, TERT, and GATA2.

• Detect point mutations, insertions/deletions, and structural variants.

• Process multiple specimen types (fresh cells, FFPE, cfDNA).

• Provide results via a secure electronic portal within 10 calendar days of sample receipt.

• Demonstrate experience supporting longitudinal clinical research studies.

• Contract Type: Firm-fixed-price purchase order.

• Period of Performance: 06/01/2026 - 5/31/2027.

• Estimated Value: Not explicitly stated, but the acquisition is not expected to exceed the simplified acquisition threshold.

• Submission Deadline: May 29, 2026, at 9:00 AM EDT.

• Submission Method: Electronically to nicholas.capobianco@nih.gov.

• Evaluation Factors: Technical Capability (most important), Past Performance, and Price. Technical capability and past performance are combined and are more important than price.

• Required Information: Unit and total price, shipping/handling costs, delivery timeframe, delivery terms, F.O.B. point, product/service description, Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification.

• NAICS Code: 621511 – Medical Laboratories.

• Small Business Size Standard: $41.5 million.

• This requirement is set aside for small business concerns.

• Offerors must be registered in the System for Award Management (SAM).

• The solicitation number is 75N98026Q00369.

• FAR 52.212-1, 52.212-2, 52.212-3, 52.212-4, and 52.212-5 apply.

Solicitation / RFP / RFQ

This is a combined synopsis/solicitation for commercial items to obtain Next Generation Sequencing (NGS) services. The National Institutes of Health (NIH) seeks to award a firm-fixed-price purchase order for services supporting clinical and research activities related to bone marrow failure syndromes, including aplastic anemia and related disorders.

• Perform genomic sequencing on patient-derived samples (peripheral blood, bone marrow, plasma, or FFPE tissue) to detect somatic and germline mutations relevant to hematologic conditions.

• Utilize a sequencing panel covering approximately 300+ genes associated with hematologic malignancies and bone marrow failure syndromes, including specific genes like UBA1, TERT, and GATA2.

• Capability to detect point mutations, insertions/deletions, and relevant structural variants.

• Ability to process multiple specimen types (fresh cells, FFPE, cfDNA).

• Standardized methodology to ensure consistency and reproducibility of longitudinal patient data.

• Demonstrated experience supporting longitudinal clinical research studies is preferred.

• Contract Type: Firm-fixed-price purchase order.

• Period of Performance: 06/01/2026 to 05/31/2027.

• Estimated Value: Not explicitly stated, but the NAICS code (621511 – Medical Laboratories) has a small business size standard of $41.5 million.

• Submission Deadline: May 29, 2026, at 9:00 AM EDT.

• Submission Method: Electronically to nicholas.capobianco@nih.gov.

• Evaluation Factors: Technical Capability (most important), Past Performance, and Price. Technical capability and past performance are more important than price.

• Required Information: Unit and total price, shipping and handling costs, delivery timeframe, delivery terms, F.O.B. point, product/service description, Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. Offerors must be registered in SAM.gov.

• This requirement is set aside for small business concerns.

• The solicitation number is 75N98026Q00369.

• Delivery Location: Services performed at contractor's facility; samples shipped from NIH, Bethesda, MD.

• Turnaround time for results: 7-10 days after receipt of samples.

Solicitation / RFP / RFQ

This is a combined synopsis/solicitation for commercial items to procure Next Generation Sequencing (NGS) services. The National Institutes of Health (NIH) seeks to award a firm-fixed-price purchase order for services supporting clinical and research activities related to bone marrow failure syndromes, including aplastic anemia and related disorders. The acquisition is conducted under FAR Subpart 12.6 for streamlined solicitation of commercial items.

• Perform genomic sequencing on patient-derived samples (peripheral blood, bone marrow, plasma, or FFPE tissue).

• Detect somatic and germline mutations relevant to hematologic conditions.

• Utilize a sequencing panel covering approximately 300+ genes associated with hematologic malignancies and bone marrow failure syndromes.

• Include clinically relevant genes such as UBA1 (VEXAS syndrome), TERT, GATA2, and related markers.

• Detect point mutations, insertions/deletions, and relevant structural variants.

• Process multiple specimen types (fresh cells, FFPE, cfDNA).

• Provide results via a secure electronic portal within 10 calendar days of sample receipt.

• Employ a standardized methodology for consistency and reproducibility.

• Contract Type: Firm-fixed-price purchase order.

• Period of Performance: 06/01/2026 to 05/31/2027.

• Estimated Value: Not explicitly stated, but the NAICS code (621511) has a small business size standard of $41.5 million.

• Submission Deadline: 05/29/2026 at 9:00 AM EDT.

• Submission Method: Electronically to nicholas.capobianco@nih.gov.

• Required Information: Unit and total price, shipping/handling costs, delivery timeframe, delivery terms, F.O.B. point, product/service description, Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. Offerors must be registered in SAM.gov.

• Evaluation Factors: Technical Capability (most important), Past Performance, and Price. Technical capability and past performance are more important than price.

• This requirement is set aside for small business concerns.

• NAICS Code: 621511 – Medical Laboratories.

• Small Business Size Standard: $41.5 million.

• Solicitation Number: 75N98026Q00369.

• Offerors must include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items.

• FAR 52.212-1, 52.212-4, and 52.212-5 apply.

• Demonstrated experience supporting longitudinal clinical research studies is preferred.