Technology InteGrator and AcceleratoR (TIGAR)

SOL #: ARPA-H-SOL-26-144Solicitation

Overview

Buyer

Health And Human Services
National Institutes Of Health
ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Washington, DC, 20005, United States

Place of Performance

Washington, DC

NAICS

Research and Development in the Physical (541715)

PSC

Health R&D Services; Health Care Services; Experimental Development (AN13)

Set Aside

No set aside specified

Timeline

1
Posted
Apr 17, 2026
2
Last Updated
Jun 1, 2026
3
Submission Deadline
Jun 8, 2026, 9:00 PM

Qualification Details

Fit reasons
  • NAICS alignment with historical contract wins in similar service areas.
  • Scope strongly matches core technical capabilities and delivery model.
Risks
  • Past performance thresholds may require one additional teaming partner.
  • Potential clarification needed on staffing minimums before bid/no-bid.
Next steps

Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.

Quick Summary

The Advanced Research Projects Agency for Health (ARPA-H) has issued an Innovative Solutions Opening (ISO) for the Technology InteGrator and AcceleratoR (TIGAR) effort. This initiative seeks foundational proofs-of-concept for stabilizing regenerative tissues and organs through enabling technologies for temperature-flexible storage. The goal is to overcome current roadblocks in storing and distributing complex biologics, reducing reliance on strictly controlled temperature zones. This is Amendment 1 to the original ISO, updating webinar and registration dates.

Scope of Work

TIGAR aims to develop new paths for stabilizing regenerative tissues and organs by seeding enabling technologies for temperature-flexible storage in increasingly larger and more complex biological systems. Solutions may involve new materials, AI/ML, high-throughput screening, biological interventions, devices, processing methods, analytical technology, and packaging. Concepts must demonstrate progress towards functional preservation of organoids, organs, organ sub-units, or 1 cm³ volumes of tissue for at least 30 days at practical temperatures. Innovations at the cellular level without a strategy for deployment in thick tissues will not be considered.

Contract & Timeline

  • Contract Type: Multiple Other Transaction (OT) Agreements are anticipated.
  • Funding: Total ARPA-H funding requested must not exceed $2 million USD per proposal over the 18-month period of performance.
  • Period of Performance: 18 months, structured into two 9-month phases with a down-select after Phase 1.
  • Submission Deadlines (Intake Group 1):
    • Solution Video due: June 8, 2026
    • Full Proposal due: August 5, 2026
  • Submission Deadlines (Intake Group 2):
    • Solution Video due: December 8, 2026
    • Full Proposal due: February 5, 2027
  • ISO Closing Date: February 5, 2027
  • Published Date: April 22, 2026

Eligibility / Set-Aside

  • Set-Aside: None specified.
  • Eligible Entities: Universities, non-profit organizations, small businesses, and other commercial entities are encouraged to respond.
  • Restrictions: Federally Funded Research and Development Centers (FFRDCs) and government entities will not be considered as prime or sub-performers unless they possess unique capabilities and all other options are exhausted. Foreign entities may participate if compliant with regulations, but not those of concern or involved in malign foreign talent recruitment programs.
  • Requirement: Proposers must be registered in SAM.gov with a valid Unique Entity Identifier (UEI).

Evaluation

Full Proposals will be evaluated based on:

  • Scientific and Technical Merit
  • Proposer's Capabilities and/or Related Experience
  • Contribution to ARPA-H Mission and Relevance to User Experience
  • Proposed Cost/Price

Additional Notes

  • A virtual webinar will be held on May 20, 2026.
  • ARPA-H will not reimburse entities for costs incurred in responding to this ISO.
  • Resource sharing is encouraged.
  • Specific requirements for intellectual property, software component standards, genomic data sharing, organizational conflicts of interest, research security, human subjects research, and vertebrate animal subjects research are detailed in the appendices.

People

Points of Contact

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Versions

Version 4
Solicitation
Posted: Jun 1, 2026
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Version 3
Solicitation
Posted: May 12, 2026
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Solicitation
Posted: Apr 22, 2026
Version 1
Solicitation
Posted: Apr 17, 2026
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Technology InteGrator and AcceleratoR (TIGAR) | GovScope