BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI) Proposers' Day
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Advanced Research Projects Agency for Health (ARPA-H), under the National Institutes of Health, has issued a Special Notice for the BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI) Proposers' Day. This event will introduce a new program focused on transforming therapeutic approaches for protein dysfunction in diseases like neurodegenerative disorders, cancers, and diabetes. The Proposers' Day is scheduled for February 20, 2026, in Washington, DC, and virtually.
Purpose & Program Scope
The BIOGAMI program seeks to develop innovative tools to predict and modulate protein misfolding and aggregation, and identify novel indicators for early detection. It aims to control protein folding to address a wide range of diseases. The program will feature two technical areas: TA1: Molecular Grammar of Intrinsically Disordered Regions (IDRs) and TA2: Modulate Intrinsically Disordered Proteins (IDPs). Proposals for the future Innovative Solutions Opening (ISO) will need to address both TAs in Phase 1.
Proposers' Day Details
This optional Proposers' Day will inform the scientific community about the BIOGAMI program's goals, scope, and anticipated proposal structure. It offers opportunities for networking, understanding the technical areas in depth, and potential collaboration. Attendees can submit a one-page "teaming profile" and optionally participate in 5-minute "Lightning Talks" to showcase capabilities.
Key Dates & Registration
- Proposers' Day Date: February 20, 2026
- Registration Opens: January 30, 2026
- Registration Closes: February 18, 2026 (in-person) / February 19, 2026 (virtual)
- Format: Hybrid event (in-person in Washington, DC, and virtual). Advance registration is required, and there is no fee to attend.
Contract & Timeline
- Type: Special Notice (pre-solicitation activity for an upcoming Innovative Solutions Opening)
- Set-Aside: None specified
- Published Date: January 27, 2026
- Contact: The BIOGAMI Team at BIOGAMI@arpa-h.gov
Additional Notes
This Special Notice is for informational and planning purposes only and does not constitute a formal solicitation.