BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI) Proposers' Day
Overview
Buyer
Place of Performance
NAICS
PSC
Set Aside
Original Source
Timeline
Qualification Details
Fit reasons
- NAICS alignment with historical contract wins in similar service areas.
- Scope strongly matches core technical capabilities and delivery model.
Risks
- Past performance thresholds may require one additional teaming partner.
- Potential clarification needed on staffing minimums before bid/no-bid.
Next steps
Validate eligibility requirements, assign capture owner, and schedule partner outreach to confirm teaming strategy before submission planning.
Quick Summary
The Advanced Research Projects Agency for Health (ARPA-H) has issued a Special Notice for a Proposers' Day for the new BIOmolecular Grammar for protein Aggregation Modulation and Intervention (BIOGAMI) program. This event, scheduled for February 20, 2026, aims to inform the scientific community about the program's goals and scope. Registration is required, with varying deadlines for in-person and virtual attendance.
Program Overview
The BIOGAMI program seeks to transform therapeutic approaches for diseases involving protein dysfunction, such as neurodegenerative disorders, cancers, and diabetes. It aims to develop tools for predicting and modulating protein misfolding and aggregation, and to identify novel indicators for early detection. The program will feature two technical areas (TA1: Molecular Grammar of IDRs, TA2: Modulate IDPs) and two phases, each 24 months long, with proposals required to address both TAs in Phase 1.
Proposers' Day Details
The Proposers' Day on February 20, 2026, will be a hybrid event held in Washington, DC. It will provide an overview of the BIOGAMI program, its technical areas, and proposal structure. Attendees can submit a one-page "teaming profile" and optionally participate in 5-minute "Lightning Talks" to showcase capabilities and identify collaborators. The event will include overview presentations, lightning talks, and private sidebar meetings. Attendance is optional and not a prerequisite for submitting a solution summary or proposal.
Contract & Timeline
- Type: Special Notice (Informational/Planning)
- Proposers' Day Date: February 20, 2026
- Registration Deadline: February 19, 2026 (virtual)
- Published: February 6, 2026
- Set-Aside: Not Applicable
Additional Notes
This notice is for informational and planning purposes only and does not constitute a formal solicitation. Questions will be addressed during a Live Q&A session, with answers posted on a FAQ page. For inquiries, contact The BIOGAMI Team at BIOGAMI@arpa-h.gov.